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EC number: 215-710-8
CAS number: 1344-95-2
Experimental studies gave no evidence of skin irritation. Slight to moderate transient irritation to the eye that may occur is not relevant for classification.
studies on calcium silicate (CS) have been located.
structure-analogous substances, synthetic amorphous sodium aluminum
silicates (NAS), failed to produce irritation of rabbits´ skin. Ocular
effects were variable in several studies: Initial conjunctival
irritation was observed following instillation of NAS powder into
rabbits´ eyes without involvement of the cornea and iris (JM Huber
1978). More pronounced effects were observed in another study (PPG
1975): The slight to moderate eye reactions were reversible within 3, 7
or 14 days.
can be concluded that based on current numerical standards of assessment
(EU, GHS), no classification is required.
Irritation to the respiratory
sytem is related to deposition of particles, but is no particular
inherent property of silica / silicates.
synthetic amorphous calcium silicate as structure-analogous substance to
NAS no classification for skin an eye irritation is required.
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