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Ecotoxicological information

Long-term toxicity to fish

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Link to relevant study record(s)

Reference
Endpoint:
adult fish: sub(lethal) effects
Data waiving:
other justification
Justification for data waiving:
other:
Conclusions:

In Annex IX of Regulation (EC) No 1907/2006, it is laid down that long-term toxicity testing shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the
effects on aquatic organisms. This is not considered to be the case. The low estiimated Kow of the substance, its very low acute toxicity (well in excess of 100 mg/L) and its rapid biodegradability do not
justify further studies. Tartrates, as well as salts of other dibasic carboxyllic acids are organic acids part of common metaboplic routes of multiple organisms and are readily taken up and degraded. See
further discussion in toxicokinetics section.
Executive summary:

In Annex IX of Regulation (EC) No 1907/2006, it is laid down that long-term toxicity testing shall be proposed by the registrant if the

chemical safety assessment indicates the need to investigate further the effects on aquatic organisms. This is not considered to be the

case. The low estiimated Kow of the substance, its very low acute toxicity (well in excess of 100 mg/L) and its rapid biodegradability do

not justify further studies. Tartrates, as well as salts of other dibasic carboxyllic acids are organic acids part of common metabollic routes

of multiple organisms and are readily taken up and degraded. See further discussion in toxicokinetics section.

Description of key information

n Annex IX of Regulation (EC) No 1907/2006, it is laid down that long-term toxicity testing shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on aquatic organisms. This is not considered to be the case. The low estiimated Kow of the substance, its very low acute toxicity (well in excess of 100 mg/L) and its rapid biodegradability do not justify further studies. Tartrates, as well as salts of other dibasic carboxyllic acids are organic acids part of common metaboplic routes of multiple organisms and are readily taken up and degraded. See further discussion in toxicokinetics section.

Key value for chemical safety assessment

Additional information