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EC number: 217-496-1
CAS number: 1873-88-7
Table 1 Effect of 1,1,1,3,5,5,5-Heptamethyltrisiloxane on the
Mobility of Daphnia magna
Mean initial measured concentration
Geometric mean measuredconcentration
Immobilizeddaphnids after24 hours
Immobilizeddaphnids after48 hours
0 (Solvent Control)
Short-term toxicity to invertebrates: 48-h EC50: >0.030 mg/l
(geometric mean measured concentration) or >0.31 mg/l (mean initial
measured concentration) (highest concentration tested) (OECD Guideline
202 (Daphnia sp. Acute Immobilisation Test)).
A 48-hour EC50 value of >0.030 mg/l has been determined
for the effects of the test substance on mobility of Daphnia magna based
on geometric mean measured concentrations.
It is likely that the test organisms were exposed to the parent
The water solubility limit of the test substance has been
determined in a separate study to be 0.02 mg/l.
A 48-hour EC50 of >100 mg/l has been determined for the
effects of trimethoxysilane (CAS: 2487-90-3) on mobility of Daphnia
magna. The test organisms will have been exposed to the hydrolysis
products of the substances. Read-across of trimethoxysilane is
not used to fulfil any data-gap, it is just used to demonstrate that
reaction of the Si-H bond does not cause toxic effects.
Taken together the data indicate that the registered substance
does not exhibit short-term toxicity to aquatic invertebrates at its
solubility limit and that Si-H further reactions with electrophilic
compounds are not likely to occur or do not affect short-term toxicity.
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