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EC number: 217-496-1
CAS number: 1873-88-7
The key study for skin sensitisation is read across from the
structurally analogous substance octamethyltrisiloxane (L3, CAS
107-51-7). The test substance was found not sensitising to the skin of
guinea-pig (RCC 1999).
The selected study is the only skin sensitisation study available for
the most relevant surrogate substance. It was carried out in accordance
with an appropriate OECD test guideline and in compliance with GLP.
No data were available for the registered substance, and therefore the
key study for the structurally analogous substance octamethyltrisiloxane
(L3, CAS 107-51-7) was used as read across.
The study was conducted according to an appropriate OECD/EU test
guideline, and in compliance with GLP. None of the test animals showed
any signs of sensitisation.
Based on the available data from the structurally analogous substance
octamethyltrisiloxane (L3, CAS 107-51-7), no classification is proposed
for the registered substance in accordance with Regulation (EC) No
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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