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EC number: 217-496-1
CAS number: 1873-88-7
Reliable short-term toxicity tests results are available for
freshwater fish (Brachydanio rerio), invertebrates (Daphnia
magna) and algae (Pseudokirchneriella subcapitata) for
1,1,1,3,5,5,5-heptamethyltrisiloxane (CAS 1873-88-7). The relevant
short-term values are:
The water solubility limit of the test substance has been
determined in a separate study to be 0.02 mg/l.
There are no long-term data for the registered substance. However,
the following data are available for the structurally-analogous
read-across substance octamethyltrisiloxane (CAS: 107-51-7):
There are no reliable data available for toxicity to
A 3 hour EC50 value of >100 mg/l (ASRI) is read-across
from the structurally-related substance L4 (CAS 141-62-8)
Trimethoxysilane (CAS 2487-90-3) is used to support short-term
toxicity to fish, aquatic invertebrates and algae endpoints, because it
has an Si-H bond that will undergo the same reaction as the registration
substance. E(L)C50 values of >100 mg/l for each species have
been determined. Read-across from trimethoxysilane is not used to fulfil
any data-gap, but is used to demonstrate that presence of the Si-H bond
does not cause toxic effects.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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