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EC number: 217-496-1
CAS number: 1873-88-7
In a GLP-compliant study carried out
according to OECD Test Guideline 405, Siloxan HSi2 was tested for its
potential to irritate the eyes of rabbits.
Three female Himalayan rabbits were each
given a 0.1 ml instillation of undiluted Siloxan HSi2 into the right
eye, with the left eye acting as an untreated control. Treated eyes were
not washed, and were examined at 1, 24, 48 and 72 hours after treatment.
After 24 hours, the eyes were examined with the aid of fluorescein.
There were no signs of irritation to the
cornea, iris or conjuctivae over the course of the study in any of the
treated rabbits. Under the conditions of this study, 0.1 ml of Siloxan
HSi2 was not irritating to the eyes of rabbits.
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