Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
other: Literature data
Adequacy of study:
other information
Study period:
1971
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Period of observation and vehicle, doses used, number and time of death at each dose, systemic response to treatment not mentioned. Non GLP study.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1971

Materials and methods

Principles of method if other than guideline:
Not stated
GLP compliance:
no
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Sodium glyoxylate

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
No data

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Details on exposure:
No data
Doses:
250, 300 and 500 mg/kg
No. of animals per sex per dose:
10
Control animals:
not specified
Details on study design:
No data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
300 mg/kg bw
Mortality:
Lethality occured within 30 minutes after a short convulsive period.
Clinical signs:
No data
Body weight:
No data
Gross pathology:
No data
Other findings:
No data

Applicant's summary and conclusion