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Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Adequacy of study:
weight of evidence
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Publication data with only few information

Data source

Reference
Reference Type:
publication
Title:
Allergic contact Dermatitis from cocoamidopropyl betaine, cocamidoamine, 3-(Dimethylamino)propylamine, and oleamidopropyl dimethylamine : Co-reactions or cross- reactions?
Author:
Moreau L. and Sasseville D.
Year:
2004
Bibliographic source:
Dermatitis. 2004 Sep;15(3):146-9

Materials and methods

Type of sensitisation studied:
skin
Study type:
case report

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Results of examinations:
In this publication, the authors reported different cases of contact dermatitis caused by amido amines derivatives used in cosmetic products. Several experiments (patch-tests) found in literature and discussed in this paper confirm that the presence of 3-dimethylaminopropylamine (a feedstock found as an impurity) could be hypothesized to explain these allergic reactions.

Applicant's summary and conclusion

Executive summary:

In this publication, the authors reported different cases of contact dermatitis caused by amido amines derivatives used in cosmetic products. Several experiments (patch-tests) found in literature and discussed in this paper confirm that the presence of 3-dimethylaminopropylamine (a feedstock found as an impurity) could be hypothesized to explain these allergic reactions.