Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

No short-term terrestrial test data is available for Amides, C18-unsatd., N-[3-(dimethylamine)propyl]. One long-term earthworm test has been performed resulting in a NOEC of 1000 mg/kg dw (Witte, 2010). Eisenia fetida were exposed to Amides, C18-unsatd., N-[3-(dimethylamine)propyl] according to OECD Guideline 222 and GLP requirements. The worms were assessed for adult worm mortality, behavioural effects and biomass development after 28 days of exposure. The reproduction rate was assessed after an additional 28 days. All study validity criteria were met. No mortality was observed in any treatment group. The body weight change of the earthworms after 4 weeks exposure was not statistically significant different compared to the control up to and including the highest test concentration of 1000 mg test item/kg soil dry weight (Dunnett's test,α = 0.05). The reproduction rates after 8 weeks exposure to Amides, C18-unsatd., N-[3-(dimethylamine)propyl] were not significantly different compared to the control up to and including the highest test concentration of 1000 mg test item/kg soil ( Dunnett's t-test,α = 0.05). No behavioural abnormalities were observed in any of the treatment groups.

There are no other data available for characterizing the effects of Amides, C18-unsatd., N-[3-(dimethylamine)propyl]

on soil organisms. The substance sorbs strongly to soil and is readily biodegradable. In addition, the test substance was observed to be not harmful to sludge micro-organisms. Further tests on soil micro-organisms do therefore not need to be conducted as no concern is indicated for the terrestrial compartment based on one long-term test result.