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Physical & Chemical properties

Partition coefficient

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Description of key information

The Log Kow (Pow) of Amides, C18-unsatd., N-[3-(dimethylamine)propyl] was determined to be 6.1 for the C18:1 carbon chain component, 5.3 for the C18:2 carbon chain component and 4.6 for the C18:3 carbon chain component. 

Key value for chemical safety assessment

Log Kow (Log Pow):
6.1
at the temperature of:
25 °C

Additional information

A partition coefficient 1-octanol/water test for Amides, C18-unsatd., N-[3-(dimethylamine)propyl] has been performed according to OECD guideline for testing of chemicals, No. 123. The test substance consisted of several components of which the C18 carbon chain components with one, two and three double bonds represent the main components. These components were analyzed for calculating the Pow results.

A summary of the results is presented below.

C18’-component

Average 6.1

C18’’-component

Average 5.3

C18’’’-component

Average 4.6

In the Chapter R.7A of the REACH guidance (Section R.7.1.8.3; Guidance on regulatory compliant Kow determination for surfactants), it is indicated that none of the experimental methods is very well suited for determining the Kow of surface active chemicals. The slow stirring method seems to be the best in theory, but still not demonstrated to be perfect. Indeed, due to the physico-chemical properties of surfactants, specifically their tendency to either accumulate at the octanol/water interface or to coat the surfaces of the above-described HPLC adsorbent phase, the logKow of surfactants cannot be accurately measured for these substances. Therefore, the log Kow values of Amides, rape-oil, N-[3-(dimethylamino)propyl]

can not be used to predict the partitioning behaviour (sorption or bioaccumulation potential) of this compound.