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EC number: 204-279-1
CAS number: 118-82-1
Mean values for endpoints
Dietary level (%)
Number females pregnant (10 bred)
Numbers in litter
Live, Day 4
When pregnant rats were given diets containing test article at
concentrations of 0.125 to 1.25% of the dry weight of the food, there
were no effects on length of gestation, size of pups, or total number of
young per litter. There was not an increase compared
to control in numbers of stillborn pups in the litters. In
comparison, feeding N,N’-diphenyl-p-phenylenediamine (DPPD) was
associated with increase in incidence of stillborns, but not an effect
on numbers of young in the litters or offspring weights. DPPD
in the basal diet with adequate vitamin E caused prolonged gestation in
3 of 10 rats which, when lengthened to 25 days, resulted in death before
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