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Ecotoxicological information

Short-term toxicity to fish

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Link to relevant study record(s)

Description of key information

An OECD 203 study is available with Bis (2-chloroethoxy)methane (the most toxic of the three main components) . This study resulted in LC50 = 50.2 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
50.2 mg/L

Additional information

One OECD 203 study is available with one the main constituents (Bis (2-chloroethoxy)methane) which is the most toxic. ECOSAR predicted values are available for the three main constituents (including Bis (2-chloroethoxy)methane)and they are as follows:

Bis (2-chloroethoxy)methane 96 hr LC50: 125.22 mg/L (compare to measured value of 50.2 mg/L)

Ethane, 1-(2-chloroethoxy)-2-[(2-chloroethoxy)methoxy: 225.23 mg/L

1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane: 96 hr LC50 = 610.849 mg/L

The predicted data show that Bis (2-chloroethoxy)methane is the most toxic of the three main components.

As a result the measured value of 50.2 mg/L is taken as the worst case and used for risk assessment purposes, without a need to perform full tests with the remaining 2 components or the complete substance mixture.