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EC number: 258-436-4
CAS number: 53220-22-7
potential of ditetradecyl peroxydicarbonate to cause damage to the
conjunctiva, iris or cornea was assessed in three New Zealand White
rabbits, each subjected to a single ocular instillation of 0.1 g of the
test material. Ocular reactions were assessed 1, 24, 48 and 72 hours
diffuse crimson-red conjunctival appearance or injection of the
conjunctival blood vessels (mean score 0.5), very slight or slight
chemosis (mean score 0.1) and discharge were observed in all rabbits
during the first 48 hours following instillation. Iritis was observed in
one rabbit at the 24 hour examination (individual score 0.3). The test
eyes of all rabbits were overtly normal at the 72 hour examination.
Instillation of the test item caused a very slight initial pain
response. Ditetradecyl peroxydicarbonate was classified as non-irritant
to the eye.
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