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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Inhalation hazard test, saturated atmosphere was tested, acceptable for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1972
Report date:
1972

Materials and methods

Principles of method if other than guideline:
Method: BASF test
GLP compliance:
no
Remarks:
GLP was not compulsatory at this time
Test type:
other: Inhalation hazard test

Test material

Constituent 1
Chemical structure
Reference substance name:
Dibenzyldimethylammonium chloride
EC Number:
202-903-7
EC Name:
Dibenzyldimethylammonium chloride
Cas Number:
100-94-7
Molecular formula:
C16H20N.Cl
IUPAC Name:
dibenzyldimethylammonium chloride
Test material form:
liquid

Test animals

Species:
rat
Strain:
other: Gassner
Sex:
not specified

Administration / exposure

Route of administration:
inhalation: vapour
Details on inhalation exposure:
To generate saturated atmosphere, air was directed though a 5 cm layer of the test material at 20°C and 100°C respectively.
Duration of exposure:
8 h
No. of animals per sex per dose:
20°C vapour: 12 animals
100°C vapour: 12 animals
Control animals:
no

Results and discussion

Effect levelsopen allclose all
Dose descriptor:
other: LT0
Remarks:
20°C vapour
Effect level:
13.75 mg/L air
Exp. duration:
8 h
Remarks on result:
other: no mortality observed
Dose descriptor:
other: LT0
Remarks:
100°C vapour
Effect level:
43.36 mg/L air
Exp. duration:
8 h
Remarks on result:
other: no mortality observed
Mortality:
No mortalities after 8-hour exposure to an atmosphere enriched with the test substance vapour generated at 20 and 100°C.
Clinical signs:
other: Irritation of mucous membranes was observed.
Gross pathology:
No adverse effects observed.

Applicant's summary and conclusion