Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Melting point / freezing point

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2009-11-16 to 2010-04-21
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
GLP study
Reason / purpose for cross-reference:
reference to other study
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
GLP compliance:
yes
Type of method:
capillary method
Key result
Melting / freezing pt.:
> 2 - < 90 °C
Atm. press.:
1 atm
Decomposition:
no
Sublimation:
no
Remarks on result:
other: The viscosity of the test substance decreased throughout the whole test beginning at 2 °C. At about 90 °C the test substance was a colourless liquid of low viscosity. Due to these observations no melting point but a melting range was stated.
Conclusions:
The experimental determined melting range of the test substance is 2 °C to 90 °C.
Executive summary:

The determination of the melting temperature of the test substance was performed by the capillary method with hot block heating.

At the start of the test at 2 °C the test substance was a highly viscous colourless non-stirrable mass. The viscosity of the test substance decreased throughout the whole test beginning at 2 °C. At about 90 °C the test substance was a colourless liquid of low viscosity. Due to these observations no melting point but a melting range was stated. The experimental determined melting range of the test substance is 2 °C to 90 °C.

Endpoint:
melting point/freezing point
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2010-04-21
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Justification for type of information:
QSAR prediction
Reason / purpose for cross-reference:
reference to other study
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
not applicable
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
not applicable
Principles of method if other than guideline:
Atom/fragment contribution method using the software MPBPWIN Version v1.43, provided by U.S. Environmental Protection Agency.
GLP compliance:
yes
Type of method:
other: Software MPBPWIN Version v1.43
Key result
Melting / freezing pt.:
33.8 °C
Conclusions:
The calculated melting point of the main constituent (3-Hydroxy-2-(hydroxymethyl)-2-methylpropionaldehyde) of the test substance using a QSAR-method is 33.8 °C.
Executive summary:

The calculated melting point of the the main constituent (3-Hydroxy-2-(hydroxymethyl)-2-methylpropionaldehyde) of the test substance

using a QSAR-method is 33.8 °C.

Description of key information

Melting Temperature ( OECD 102, EU Method A.1.) The experimental determined melting range of the test substance is 2 °C to 90 °C. 

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
33.8 °C

Additional information

The determination of the melting temperature of the test substance was performed by the capillary method with hot block heating.

At the start of the test at 2 °C the test substance was a highly viscous colourless non-stirrable mass. The viscosity of the test substance decreased throughout the whole test beginning at 2 °C. At about 90 °C the test substance was a colourless liquid of low viscosity. Due to these observations no melting point but a melting range was stated. The experimental determined melting range of the test substance is 2 °C to 90 °C.

In addition a supporting study was performed using a QSAR method. The calculated melting point of the the main constituent 3-Hydroxy-2-(hydroxymethyl)-2-methylpropionaldehyde)of the test substance using a QSAR-method is 33.8 °C.