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EC number: 701-281-9 | CAS number: -
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2013-07-25 to 2013-09-04
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Dissociating properties:
- not determined
- Conclusions:
- The dissociation constant could not be determined.
- Executive summary:
The dissociation constant was determined using the titration method.
The 0.1M sample solution (in water) was found to be close to neutral in pH tending more towards the acidic region. When titrated against both acid and base, the inflection point was reached instantly in both cases. Smaller additions were used when titrating; however the inflection point was still reached instantly. Testing therefore could not be carried out.
Reference
The 0.1M sample solution (in water) was found to be close to neutral in pH tending more towards the acidic region. When titrated against both acid and base, the inflection point was reached instantly in both cases. Smaller additions were used when titrating; however the inflection point was still reached instantly. Testing therefore could not be carried out.
The 0.1M solutions were used due to the neutral pH of the test sample. Lower concentrations would simply display the pH of the water it was added to.
Description of key information
Dissociation constant (OECD 112): The dissociation constant could not be determined.
Key value for chemical safety assessment
Additional information
The dissociation constant was determined using the titration method.
The 0.1M sample solution (in water) was found to be close to neutral in pH tending more towards the acidic region. When titrated against both acid and base, the inflection point was reached instantly in both cases. Smaller additions were used when titrating; however the inflection point was still reached instantly. Testing therefore could not be carried out.
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