Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

Two in vitro genotoxicity test were performed, covering the endpoints gene mutation in bacteria and chromosome aberrations in mammalian cells. Both tests were positive.

One in vivo genotoxicity test was performed, covering the endpoint cytogenicity. The test was negative.

Short description of key information:
Bacterial Reverse Mutation Assay: OECD 471, EU method B.13/14: mutagenic
In vitro Mammalian Chromosome Aberration Test: OECD 473, EU method B.10: clastogenic
Bone marrow micronucleus test in rats: OECD 474: negative

Endpoint Conclusion:

Justification for classification or non-classification

No classification is derived from the results of the genotoxicity tests.

Categories Display