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EC number: 205-252-7
CAS number: 136-60-7
An evaluation of the inherent properties of butyl benzoate is
performed against the ANNEX XIII criteria. If insufficient data were
available, the screening criteria as laid down in ECHA Guidance on
information requirements and chemical safety assessment Chapter R.11:
PBT Assessment (2014) were applied.
The persistency assessment is based on the screening criteria in
Annex XIII of the REACH Regulation. The biodegradation potential of the
test substance has been assessed in a guideline study on ready
biodegradability following the OECD 301B (IES, 2018). A 28-d ready
biodegradability test (OECD 301F) using unadapted activated sludge from
a predominantly domestic waste water treatment plant indicated that
butyl benzoate was readily biodegradable under the conditions of the
test (initial concentration 100 mg/L). The test substance showed 74%
biodegradation (test bottle 1 and 2, respectively, based on % ThCO2). It
can therefore be concluded that based on the criteria mentioned above
the substance is not persistent in the environment. The substance is
concluded to be not P/vP.
The bioaccumulation assessment is based on the screening criteria
in Annex XIII of the REACH Regulation.The available evidence on the
bioaccumulation potential for the substance indicates that the screening
criteria for bioaccumulation potential (B and vB) are not met. Based on
a log Pow of 3.30 at neutral pH, a low BCF can be estimated. Since the
log Pow of the substance is < 4.5, the screening criteria for
bioaccumulation are not fulfilled and the substance is concluded not to
have a bioaccumulative potential (not B / not vB).
The toxicity assessment is based on the screening criteria in
Annex XIII of the REACH Regulation. Based on an OECD 201 study (Envigo,
2018) it is concluded that the test item does not meet the Toxic (T)
criteria since the EC10 was 1.5 mg/L. The test substance is not
classified as carcinogenic (Cat. 1 or 2), as mutagenic (Cat. 1 or 2), or
as reproductive toxicant (Cat. 1, 2, or 3), nor as STOT RE Cat. 1 or 2
according to the Regulation EC N° 1272/2008. Hence, it does not fulfill
the criteria to be considered as Toxic (not T).
Taking into account the conclusions that the substance is not
P/vP, not B/vB and not T, the substance should not be considered as a
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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