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EC number: 218-235-4
CAS number: 2090-05-3
The chronic toxicity study of the test
substance was examined in Fischer 344 rats. The test substance was
administered in the diet for 18 to 24 months at two dose levels.
No adverse clinical signs directly
attributable to the compound were observed in treated animals.
Differences in the average body weight, and mortality rates between
treated and control groups were negligible. The results of the
statistical test for dose-related trends were significant (p<0.05).
Although a variety of tumors occurred among test and control rats of
each sex, tumors appearing in treated rats were similar in type and
number to those in controls. It was concluded that no evidence of
carcinogenicity in rats from the test substance was demonstrated.
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