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EC number: 218-235-4
CAS number: 2090-05-3
No acute toxicity studies with calcium dibenzoate are available,
thus the acute toxicity will be addressed with existing data on the
dissociation products as detailed in the table below.
Signs of acute oral or acute dermal toxicity are not expected for
calcium dibenzoate, since the two moieties calcium and benzoate
respectively benzoic acid have not shown signs of acute oral or acute
dermal toxicity in in vivo testing (both LD50 > 2000 mg/kg bw). Under
the assumption that the moieties of calcium dibenzoate show their
toxicological profile individually upon dissolution, an acute toxicity
estimates (ATE) for the acute oral and dermal (systemic) toxicity of
calcium dibenzoate can be calculated using the equation given in
regulation (EC) 1272/2008, Annex I, Section 188.8.131.52.1.
A study for acute toxicity via inhalation was not conducted with
calcium dibenzoate, since it is produced and placed on the market in a
form in which no inhalation hazard is anticipated, thus acute toxic
effects are not likely to occur during manufacture and handling of that
substance. For further information on the toxicity of the individual
moieties, please refer to the relevant sections in the IUCLID and CSR.
Based on in vivo oral and dermal LD50 data on the moieties, acute
toxicity estimates for calcium dibenzoate have been calculated resulting
in LD50 values > 2000 mg/kg bw. There are no indications on narcotic
effects or respiratory irritation.
According to the criteria of REGULATION (EC) No 1272/2008 and its
subsequent adaptions, Calcium dibenzoate does neither have to be
classified and has no obligatory labelling requirement for acute oral or
dermal toxicity nor for specific target organ toxicity after single
exposure (STOT SE).
Calcium dibenzoate is not classified for acute inhalative toxicity
because of lacking data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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