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EC number: 942-523-5
CAS number: 2156594-77-1
No study is available in which the toxicokinetic properties
(distribution, metabolism, elimination) of dipropylheptylcarbonate were
The expected toxicokinetic behaviour is derived from the
physicochemical properties, the results from the available toxicological
studies and the available literature following the information given in
guidance document 7c.
Fatty acids, C12 -14, alphasulfo, disodium salts having a
molecular weight of ~340 g/mol is a liquid with a water solubility of
>63,35 g/L (20°C) . It has a low volatility of <1,1*10 -4 Pa (20°C) and
a lipophilic character (log Pow <-2,1).
Oral and GI absorption:
Substance is soluble in water and in GI fluids. It will easily
pass through aqueous pores or epithelial barriers. The substance may be
taken up by micellular solubilisation.
Substance is easily soluble in mucus and does easily pass through
aqueous pores or epithelial barriers. An absorption via the lung is
Due to the physico chemical information, the substance will not
easily absorbed via the skin. A low transfer between the stratum corneum
and the epidermis is limited. As a consequence the systemic availablity
should be low after dermal exposure.
The molecular weight points to a wide distribution.
A accumulation is not expected.
Metabolism:No detailed information can be
derived concerning the metabolism.
Reactivity:Available studies on
genotoxicity were negative, i. e. there is no indication of a reactivity
of the substance or its metabolites under the test conditions.
Due to the physico chemical information an excretion of the
substance via the urine is plausible. An exalation is not assumed due to
the low vapor pressure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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