3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride

Density

Link to relevant study record(s)

Reference

Endpoint:

density, other

Remarks:

density

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard test guidelines

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Principles of method if other than guideline:

The density of Test item 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1Hpyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride (CAS No. 68391-31-1 )was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014 .

GLP compliance:

no

Type of method:

pour and tap (for solids)

Key result

Type:

pour density

Density:

0.257 g/cm³

Temp.:

24 °C

Remarks on result:

other: No other detail available

Key result

Type:

tap density

Density:

0.334 g/cm³

Remarks on result:

other: at 972.1 hPa.

TEST ITEM DESCRIPTION AND RESULTS :

FOR SOLIDS:

By Pour Density and Tapped Density Method:

Method Details		Observations		Remarks if, any
Guideline	OECD 109	1st Reading	2nd Reading
Method	Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014
Principle of method	Pour Density: It is the ratio of known weight of test item and its volume in graduated glass cylinder. Tap Density: It is the difference between the volume of test item measured before & after tapping in the graduated glass cylinder.
Test temperature (°C)		26.8°C	28.0°C
Atmospheric pressure (in hPa)		972.9 hPa	971.4 hPa
Weight of test item(m)		10.009	10.015
Volume of measuring cylinder; readability in g		250 ml;2ml	250 ml;2ml
Volume of test item without tapping (V)		40 ml	38 ml
Volume of test item after tapping ( V1)	After 10 tapping	34 ml	34 ml
	After 50 tapping	30 ml	30 ml
	After 100 tapping	30 ml	30 ml
	After 250 tapping	-	-
	After 500 tapping	-	-
	After 750 Tapping	-	-

CALCULATIONS:

FOR SOLIDS:

By Pour Density and Tapped Density Method:

Parameters	Details	Calculated values		Average Density
		1st Calculation	2nd Calculation
Pour Density of test Item (g/cm³)	= m V	10.009 /40=0.2502	10.015/38=0.2635	0.2568
Tap density of test Item (g/cm³)	= m V1	10.009/30=0.3336	10.015/30 =0.3338	0.3337

Conclusions:

The mean pour density and tapped density of 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1Hpyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride (CAS No. 68391-31-1) was determined to be 0.2568 g/cm³ and 0.3337 g/cm³at 27.4 °C and 972.1 hPa.

Executive summary:

The mean pour density and tapped density of 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1Hpyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride (CAS No. 68391-31-1) was determined to be 0.2568 g/cm³ and 0.3337 g/cm³at 27.4 °C and 972.1 hPa.

Description of key information

The mean pour density and tapped density of 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1Hpyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride (CAS No. 68391-31-1) was observed to be 0.2568 g/cm³ and 0.3337 g/cm³at 27.4 °C and 972.1 hPa.

Additional information

The mean pour density and tapped density of 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1Hpyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride (CAS No. 68391-31-1) was observed to be 0.2568 g/cm³ and 0.3337 g/cm³at 27.4 °C and 972.1 hPa.