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EC number: 252-104-2
CAS number: 34590-94-8
DPGME was applied to the backs of 200 unselected human subjects, 100
males and 100 females, and allowed to remain in direct contact with the
skin for 5 days. Three weeks later, DPGME was again applied to the backs
of the same subjects and allowed to remain in contact with the skin for
a period of 48 hours.
was tested by a repeated insult method on 50 unselected human subjects,
25 males and 25 females. The material was applied to the back of each
subject for 4 to 8 hours every other day until 10 applications had been
made. After a lapse of 3 weeks, the material was reapplied for a period
of 24 to 48 hours.
conclusion DPGME (DOWAMOL 50B) was classified as neither a primary skin
irritant nor a skin sensitizer as none of the human subjects exhibited
any evidence of irritation during the study.
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