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EC number: 203-911-3
CAS number: 111-82-0
A total of
80 rats (40 males and 40 females) Sprague-Dawley rats,Crl
allocated to four groups, three of which received the test item,
Heptadecanoic Fatty Acid Methyl Ester (C16-C18)
while the other group received the vehicle (corn oil) by oral route
(gavage) once daily under a dosage volume of 5 mL/kg. Animals will be
dosed for 2 weeks prior to pairing, during pairing, during gestation and
until at least day 4 post-partum for females or until sacrifice
for non pregnant females and until necropsy for males following 4 weeks
following dose-levels were used:
. Group 1
(10 males and 10 females): 0 mg/kg/day,
. Group 2
(10 males and 10 females):100mg/kg/day,
. Group 3
(10 males and 10 females):300mg/kg/day,
. Group 4
(10 males and 10 females):1000mg/kg/day.
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