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EC number: 238-778-0 | CAS number: 14726-36-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- Minor restrictions in design and/or reporting but otherwise adequate for assessment.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- yes
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances):
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): DMSO - Test organisms (species):
- Poecilia reticulata
- Details on test organisms:
- TEST ORGANISM
- Common name: guppy
- Source: Akzo Research Laboratories Arnhem, dpt. CRL.
- Age at study initiation: Young fish
- Length at study initiation: ≤ 2 cm
- The fish were kept at 23 ± 2 ºC - Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Post exposure observation period:
- None
- Hardness:
- 13°dH
- Test temperature:
- 23 ± 2°C
- pH:
- approximately 8.2
- Salinity:
- Not applicable
- Nominal and measured concentrations:
- Not known
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 2L glass aquaria
- Material, size, headspace, fill volume: 2 l glass aquaria filled with 1 l of test medium.
- Aeration: The medium was aerated before use.
- No. of organisms per vessel: 7-10 fish per concentration
- Renewal rate of test solution : The test medium was refreshed after 48 hours.
- Biomass loading rate: The loading in the glass test vessels was approximately 0.6 g biomass/l.
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Synthetic medium, Dutch Standard Water according to NPR 6507
- Containing: 100 mg NaHCO3/l, 20 mg KHCO3/l, 200 mg CaCl2.2H2O/l and 180 mg MgSO4.7H2O/l
- Preparation of the test medium: A stock solution in DMSO was made, from which a second stock solution in dilution water was prepared. - Reference substance (positive control):
- no
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- - Mortality of control: ≤ 10%
Reference
Description of key information
The 96-h LC50 of > 10 mg/L in Poecilia reticulata.
Key value for chemical safety assessment
Additional information
One short-term toxicity study with freshwater fish is available for zinc bis(dibenzyldithiocarbamate). The test is a semi-static non-GLP, OECD 203 guideline study with Poecilia reticulata without analytical monitoring (Akzo Nobel Research Laboratories, 1991). The 96-h LC50 value is >10 mg/L.
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