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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
July 1995
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
column elution method
Key result
Water solubility:
2.3 µg/L
Conc. based on:
test mat.
Incubation duration:
26 h
Temp.:
20 °C
pH:
7.5
Remarks on result:
other: mean value based on the flow rates. See 'Any other information on results incl. tables'.
Details on results:
The results are tabulated in 'Any other information on results incl. tables'

Table: Water solubility results

Sample

Time (hours)

pH

Test item concentration (µg/L)

Flow rate of 25 mL/h

Flow rate of 12.5 mL/h

1

1

7.5

(1.87)*

(1.87)

2

2

(1.92)

(1.64)

3

3

2.57

(1.70)

4

4

2.38

2.15

5

5

2.96

1.87

6

6

2.61

2.05

7

22

2.12

1.86

8

23

2.37

1.68**

9

24

2.80

2.32

10

26

2.55

2.09

Mean values for each column

2.53

2.06

Mean value

2.30

* Unretained value (differ by more than ± 30%)

** Outlier value

Conclusions:
The water solubility of the substance was determined to be 2.30 µg/L using the column elution method in accordance with OECD TG 105 and in compliance with GLP.

Description of key information

The water solubility of the substance was determined to be 2.30 µg/L using the column elution method in accordance with OECD TG 105 and in compliance with GLP.

Key value for chemical safety assessment

Water solubility:
2.3 µg/L
at the temperature of:
20 °C

Additional information