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EC number: 238-778-0
CAS number: 14726-36-4
data on carcinogenicity of zinc bis(dibenzyldithiocarbamate) (ZBEC) are
available. In accordance with Column 2 of REACH Annex X, a
carcinogenicity study may be proposed if the substance is classified as
mutagen category 3 or there is evidence from the repeated dose studies
that the substance is able to induce hyperplasia and/or pre-neoplastic
lesions. Available data on ZBEC indicate that the substance is not
genotoxic in vivo. In the 13-week oral study with no evidence of
pre-neoplastic lesions or hyperplasia was found. Therefore, it is
concluded that ZBEC is not carcinogenic and the performance of a
carcinogenicity study is not indicated.
Based on the lack of genotoxic potential of
zinc bis(dibenzyldithiocarbamate) (ZBEC) and repeated dose toxicity data,
classification of ZBEC for carcinogenicity is not warranted in
accordance with Directive
67/548/EEC and EU
Classification, Labelling and Packaging of Substances and Mixtures (CLP)
Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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