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EC number: 203-815-1
CAS number: 110-91-8
No data available
JUSTIFICATION FOR DATA WAIVING
No studies on the long-term reproductive toxicity to birds are available for the substance.
In Annex X Section 9.6.1 of Regulation (EC) No 1907/2006, it is laid down that any need for testing should be carefully considered taking into account the large mammalian dataset that is usually available at this tonnage level. In case of morpholine (CAS 110-91-8) a mammalian dataset is available. In addition, the hazard assessment of the substance reveals neither a need to classify the substance as hazardous according to Regulation EC 1272/2008 and its second adaptation 286/2011, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment.
The substance is not supposed to be directly applied to soil. An indirect exposure to soil via sewage sludge transfer is unlikely since the substance is readily biodegradable (for details see IUCLID Ch. 5.2.1). For a substance being considered as „readily biodegradable“, it can be assumed that it will be biodegraded within the STP process and as a consequence a transfer to the soil compartment is not expected. Based on the low measured and estimated BCF values, bioaccumulation in organisms is not to be expected (see IUCLID Ch. 5.3.1).
Hence, secondary poisoning is of no concern.
Therefore, and for reasons of animal welfare, no tests on birds are performed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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