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Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 98-42-0
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-DK-EPA

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling Database
Principles of method if other than guideline:
Skin irritation (Severe vs mild). Multicase model.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-amino-4-methoxybenzenesulphonic acid
EC Number:
202-667-5
EC Name:
3-amino-4-methoxybenzenesulphonic acid
Cas Number:
98-42-0
Molecular formula:
C7H9NO4S
IUPAC Name:
3-amino-4-methoxybenzenesulfonic acid

Test animals

Species:
other: no data
Strain:
not specified

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified
Duration of treatment / exposure:
no data
Observation period:
no data
Number of animals:
no data

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Basis:
mean
Reversibility:
no data
Remarks on result:
other: Not irritant

Applicant's summary and conclusion

Conclusions:
3-amino-4-methoxybenzenesulphonic acid is estimated to be non irritating to skin
Executive summary:

3-amino-4-methoxybenzenesulphonic acid is estimated to be non irritating to skin

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