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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Biodegradation in water:

3-acetamido-5-amino-4-hydroxybenzenesulphonic acid is 50% biodegradable in water in 38 days (half-life). This value indicates that 3-acetamido-5-amino-4-hydroxybenzenesulphonic acid is readily biodegradable in water since the half life is not more than the EPA criteria of >= 60 days (to qualify the chemical as persistent).

Also from the other weight of evidence study it is found that the substance is 69.9% degradable in 28 days which also supports the classification of the substance as not persistent in water.

Hence, it can be concluded that the substance 3-acetamido-5-amino-4-hydroxybenzenesulphonic acid is not persistent in water

Endpoint value unit Days


 % degradation 50  %   in 38days
 2  %degradation  69.9  %  in 28 days

Biodegradation in water and sediments:

Based on level III fugacity model the half life period of3-acetamido-5-amino-4-hydroxybenzenesulphonic acidwas estimated.

Half life period of3-acetamido-5-amino-4-hydroxybenzenesulphonic acidin water was observed to be 38 days while in sediment it is 340 days.

Based on these half life values it is concluded that3-acetamido-5-amino-4-hydroxybenzenesulphonic acidis readily biodegradable (non persistent) in water where as it is non biodegradable (persistent) in sediment. However it can be observed that3-acetamido-5-amino-4-hydroxybenzenesulphonic aciddoes not diffuse in the sediment medium since its percentage in the sediment medium is reported to be 0% and hence persistence in the sediment medium is not likely to be critical


Half life(days)

Percent in each medium







Biodegradation in soil:

The PBT Profiler & EPI Suite has estimated that 3-acetamido-5-amino-4-hydroxybenzenesulphonic acid is expected to be found predominantly in soil and its persistence estimate is based on its availability in this medium. Its half-life in soil, 1800 hrs (75 days). This exceeds the EPA criteria of >= 2 months (and <= 6 months). Therefore, 3-acetamido-5-amino-4-hydroxybenzenesulphonic acid is estimated to be persistent in the soil environment.


Half life(days)

Percent in each medium