Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 401-300-8 | CAS number: 86168-95-8
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Significant accumulation in organisms is not to be expected.
Key value for chemical safety assessment
Additional information
Experimental data on the bioaccumulation potential is not available. However, according to three different QSAR calculations (US EPA T.E.S.T., US EPA EPISuite and Catalogic) the substance is not expected to bioaccumulate in organisms.
US EPA T.E.S.T. v4.01 (Consensus method):
- BCF = 4.03
US EPA EPISuite v4.10 (BCFBAF v3.01):
- BCF = 3.16 L/kg wet-wt
Catalogic v5.11.2 (BCF base-line model v02.05; out of parametric domain, 62.79 % in structural domain, 100 % in mechanistic domain)
- BCF = 7.43
Furthermore, according to ECHA's guidance on information requirements and chemical safety assessment R.11 an average maximum diameter of greater than 1.7 nm plus a molecular weight of greater than 1100 can be used within a weight of evidence approach to show that a chemical may be considered as not B (BCF < 2000). The molecular weight of the substance is 1197.94 and its Dmax aver is 2.5 nm. Taken these data into account, it is not to be expected that the substance has a significant potential to bioaccumulate.
In conclusion, the substance is not expected to bioaccumulate in organisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
