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EC number: 433-400-2 | CAS number: -
An acute eye irritation/corrosion study was performed with White New Zealand Rabbit acc. to OECD Guideline 405.
Mean scores of 24 through 72 hours after ocular administration indicated moderate circumcorneal hyperemia of the iris in one rabbit. Conjunctival hyperemia with injected blood vessels was noted in all rabbits and above normal swelling of eye lids in one rabbit. The observed eye reactions were completely reversible in all rabbits within 2 days. All animals survived to the scheduled sacrifice. There were no remarkable in-life observations.
Since the mean irritation scores 24 to 72 hours after instillation were below the thresholds defined in Commission Directive 93/21/EEC (18th adaptation to technical progress of Council Directive 67/548/EEC), classification of CA 2342 A (Intermediate of CGA 293343) as to its eye irritating properties is not required. This classification still applies to the recent versions of both UN-GHS and EU-GHS (CLP).
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