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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Referred in a recognized source of peer reviewed scientific data on chemicals

Data source

Reference
Reference Type:
publication
Title:
National toxicology program technical report series no. 310: Toxicology and carcinogenesis studies of marine diesel fuel and JP-5 navy fuel in B6C3Fl mice (dermal studies).
Author:
NTP
Year:
1986
Bibliographic source:
Research Triangle Park, NC: National Toxicology Program/ National Institutes of Health. NIH publication no. 86-2566.

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
other: Acute Dermal exposure (Single application)
Principles of method if other than guideline:
Acute Dermal exposure (Single application)
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
marine diesel fuel
IUPAC Name:
marine diesel fuel
Details on test material:
mixture of hydrocarbons containing 12.7% paraffins, 43.7% naphthalenes, and 43.6% aromatic compounds

Results and discussion

Any other information on results incl. tables

Study results:

 

No substance-related signs of toxicity were observed

Applicant's summary and conclusion

Conclusions:
no irritating effects after single dermal application