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EC number: 222-321-7 | CAS number: 3425-61-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
There is no test performed with Tert-amyl hydroperoxide. The acute toxic effects on fish are read-across from data obtained with 1,1,3,3 -Tetramethylbutyl hydroperoxide. An OECD 236 non-GLP screening study is available. The 96h-LC50 for zebrafish embryos is 24 mg/L (nom.). From the algae study it is known that the substance is not stable over time, therefore a correction to 47% (mean measured conc. in the 72h algae study) of the nominal concentration is made. The corrected 96h-LC50 for fish is then 11.3 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 11.3 mg/L
Additional information
An OECD 236 non-GLP screening study is available. The 96h-LC50 for zebrafish embryos is 24 mg/L (nom.). From the algae study it is known that the substance is not stable over time, therefore a correction to 47% (mean measured conc. in the 72h algae study) of the nominal concentration is made. The corrected 96h-LC50 for fish is then 11.3 mg/L.
This result is considered worst case and is supported by an acute fish result of an analogous substance (tert-butyl hydroperoxide, CAS 75 -91 -2) This substance has a 96h-LC50 for fish of 56.9 mg/L which is in the same order of magnitude as 1,1,3,3-Tetramethylbutyl hydroperoxide. Furthermore, QSAR estimates have been provided for both 5809-08-5 and 75-91-2 for qualitative supporting evidence.
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