Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

There is no test performed with Tert-amyl hydroperoxide. The acute toxic effects on fish are read-across from data obtained with 1,1,3,3 -Tetramethylbutyl hydroperoxide. An OECD 236 non-GLP screening study is available. The 96h-LC50 for zebrafish embryos is 24 mg/L (nom.). From the algae study it is known that the substance is not stable over time, therefore a correction to 47% (mean measured conc. in the 72h algae study) of the nominal concentration is made. The corrected 96h-LC50 for fish is then 11.3 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
11.3 mg/L

Additional information

An OECD 236 non-GLP screening study is available. The 96h-LC50 for zebrafish embryos is 24 mg/L (nom.). From the algae study it is known that the substance is not stable over time, therefore a correction to 47% (mean measured conc. in the 72h algae study) of the nominal concentration is made. The corrected 96h-LC50 for fish is then 11.3 mg/L.

This result is considered worst case and is supported by an acute fish result of an analogous substance (tert-butyl hydroperoxide, CAS 75 -91 -2) This substance has a 96h-LC50 for fish of 56.9 mg/L which is in the same order of magnitude as 1,1,3,3-Tetramethylbutyl hydroperoxide. Furthermore, QSAR estimates have been provided for both 5809-08-5 and 75-91-2 for qualitative supporting evidence.