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EC number: 222-321-7 | CAS number: 3425-61-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
There is no test performed with Tert-amyl hydroperoxide. The acute toxic effects on fish are read-across from data obtained with 1,1,3,3 -Tetramethylbutyl hydroperoxide. An OECD 236 non-GLP screening study is available. The 96h-LC50 for zebrafish embryos is 24 mg/L (nom.). From the algae study it is known that the substance is not stable over time, therefore a correction to 47% (mean measured conc. in the 72h algae study) of the nominal concentration is made. The corrected 96h-LC50 for fish is then 11.3 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 11.3 mg/L
Additional information
An OECD 236 non-GLP screening study is available. The 96h-LC50 for zebrafish embryos is 24 mg/L (nom.). From the algae study it is known that the substance is not stable over time, therefore a correction to 47% (mean measured conc. in the 72h algae study) of the nominal concentration is made. The corrected 96h-LC50 for fish is then 11.3 mg/L.
This result is considered worst case and is supported by an acute fish result of an analogous substance (tert-butyl hydroperoxide, CAS 75 -91 -2) This substance has a 96h-LC50 for fish of 56.9 mg/L which is in the same order of magnitude as 1,1,3,3-Tetramethylbutyl hydroperoxide. Furthermore, QSAR estimates have been provided for both 5809-08-5 and 75-91-2 for qualitative supporting evidence.
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