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EC number: 222-321-7
CAS number: 3425-61-4
OECD 111, GLP, key study, validity 1: no potential for hydrolysis.
One key study is available to assess the
hydrolysis potential of the test substance. The hydrolysis as a function
of pH was assessed according to the OECD Guideline 111 with GLP
statement. The objective of the study was to determine the rate of
hydrolysis of the test substance in different buffers and at different
The preliminary test showed that the test
item was stable at pH 4, 7 and 9 at 50°C during 5 days but at pH 1.2,
hydrolysis reached 13.6% in the same conditions. Based on this result, a
definitive test was conducted at pH 1.2 and at 37°C for 2 and 4 hours.
No hydrolysis of the 0.01 M test item (1.04 g/L) was observed in these
In conclusion, the test substance has no
potential for hydrolysis.
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