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EC number: 223-754-4
CAS number: 4051-63-2
no data of acute toxicity on fish, daphnia and algae for the described
pigment are available, a read-across to a similar pigment (CAS 81-77-6)
is used to cover these endpoints. Since the molecular structure and the
physico-chemical properties of the pigments are very similar, the
available studies are sufficient to cover the aquatic toxicity endpoints.
Both pigments are of low solubility in water and in octanol. They do not
contain functional groups that are susceptible to pH dependent
hydrolysis at environmentally relevant pH. The pigments are generally
not readily biodegradable and additionally adsorption to the solid soil
phase is not expected. Due to the low logPow and the high molecular
weight of the pigments, bioaccumulation is not expected. Therefore, this
read-across approach is in accordance with Regulation (EC) No 1907/2006,
Annex XI, 1.5. Grouping of substance and read-across approach as it is
explained within the analogue justification in the Annex.
the analogue substance acute aquatic toxicity data on all three trophic
levels are available. This includes a study for the acute toxicity on
the golden orfe Leuciscus idus, one study on the mortality of the
waterflea Daphnia magna and one study of the toxicity on the
green algae Desmodesmus subspicatus. After exposure to the
pigment, no effects on aquatic organisms occurred within the range of
water solubility. These results confirm the expectation, that the
described pigment is considered to be essentially not bioavailable, due
to the large molecular size together with the negligible low solubility.
data on long-term toxicity are available. The hazard assessment of the
substance reveals neither a need to classify the substance as dangerous
to the environment, nor is it a PBT or vPvB substance, nor are there any
further indications that the substance may be hazardous to the
environment. Therefore, and for reasons of animal welfare long-term
toxicity testing in fish and daphnia is not provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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