4,4'-diamino[1,1'-bianthracene]-9,9',10,10'-tetraone

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2011

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Qualifier:

according to guideline

Guideline:

other: OECD Guideline 105 and ETAD Guideline

Principles of method if other than guideline:

The partition coefficient was estimated based on the ratio of the solubilities in n-octanol and in water.
The individual solubilities were determined by the flask method based on OECD Guideline 105 and the ETAD method.

GLP compliance:

no

Type of method:

estimation method (solubility ratio)

Partition coefficient type:

octanol-water

Analytical method:

high-performance liquid chromatography

Key result

Type:

log Pow

Partition coefficient:

0

Temp.:

20 °C

Remarks on result:

other: no data on pH

Details on results:

Detailed results:
3 independent vials from each solubility test were injected and measured. Each result given in the table below is the average of these 3 measurements.
The solubility in n-octanol and in water is 25 µg/L.

Estimation of log Pow:

Pow= c(n-octanol) / c( water)= 25 µg/L / 25 µg/L= 1

Log Pow= 0

Conclusions:

The partition coefficient of test substance was estimated to be log Pow= 0 at 23°C.

Description of key information

Estimated based on solubility ratio:

log Pow= 0 at 23°C

Key value for chemical safety assessment

Log Kow (Log Pow):

0

at the temperature of:

23 °C

Additional information

The partition coefficient was estimated based on the ratio of the solubilities in n-octanol and in water.

The individual solubilities were determined by the flask method based on OECD Guideline 105 and the ETAD method. The quantification was analyzed by HPLC-UV.