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Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Using read across data from a good quality OECD 406 GPMT study (Rel 2, GLP), no sensitisation effects were reported in any of the animals tested. (Driscoll 199b).

In a well conducted skin sensitisation study using an adjuvant method (GPMT,OECD 406, Rel 2, GLP) Nafol 2022 did not show any responses in guinea pigs following induction and challenge (Intradermal, occlusive method). (RTC 2000)


Migrated from Short description of key information:
Using read across data from a good quality OECD 406 GPMT study (Rel 2, GLP), no sensitisation effects were repoted in any of the animals tested.

Justification for selection of skin sensitisation endpoint:
Read across from good quality study (Octadecanol, Rel 2, OECD 406)

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

On the basis of read across data from a good quality OECD 406 GPMT study, Isostearyl alcohol would not fulfil the criteria for classification under CLP Regulation (1272/2008). It is therefore not classified as a skin sensitiser.