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EC number: 500-465-4 | CAS number: 160901-28-0 1 - 2.5 moles ethoxylated
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.106 mg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.071 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.011 mg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 000 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.384 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.038 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 7.5 mg/kg soil dw
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
According to Article 13 of Regulation (EC) No. 1907/2006 "General Requirements for Generation of Information on Intrinsic Properties of substances", information on intrinsic properties of substances may be generated by means other than tests e.g. from information from structurally related substances (grouping or read-across), provided that conditions set out in Annex XI are met.
Annex XI, "General rules for adaptation of this standard testing regime set out in Annexes VII to X” states that “substances whose physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity may be considered as a group, or category of substances. This avoids the need to test every substance for every endpoint”.
Since the group concept is applied to the members of the AES category, data will be generated from a representative category member to avoid unnecessary animal testing. Additionally, once the group concept is applied, substances will be classified and labeled on this basis.
Classification related key information for AES (C9 -11, 1-2.5EO) Na (CAS 160901-28-0):
Biodegradation in water: readily biodegradable (ISO 14593)
Bioaccumulation: no potential to bioaccumulate; log Kow < -0.858
Water solubility: > 400 g/L at 20 ºC (OECD 105)
Acute toxicity:
- For fish: 96 h LC50 (Danio rerio) = 7.1 mg a.i./L (nominal, OECD 203)
- For invertebrates: 48 h EC50 (Daphnia magna, immobilization) = 91 mg a.i./L (nominal, OECD 202)
- For algae: 72 h ErC50 (Pseudokierchnerialla subspicata, growth rate) > 100 mg a.i./L (nominal, OECD 201)
Chronic toxicity:
- For invertebrates: 21 d NOEC (Daphnia magna, reproduction): = 5.3 mg a.i./L (measured, OECD 211)
- For algae: 72h NOErC (Pseudokierchneriella subspicata, growth rate) = 31.3 mg a.i./L (nominal, OECD 201)
Classification justification according to CLP of AES (C9 -11, 1-2.5EO) Na (CAS 160901-28-0):
Based on the data above, AES (C9 -11, 1-2.5EO) Na is considered to be rapidly degradable and has a low potential for bioaccumulation. The acute aquatic toxicity L(E)C50 are above 1 mg/L for fish, invertebrates and algae. Valid chronic toxicity data are available to aquatic invertebrates and algae – the lowest NOEC is 5.3. mg/L (thus not in the range of > 0.1 to < 1 mg/L) for aquatic invertebrates. AES (C9 -11, 1-2.5EO) Na (CAS 160901-28-0) does not need to be classified and labeled as environmental hazard according to the Regulation (EC) No.1272/2008 (CLP) and the Regulation (EU) No. 286/2011 (2nd ATP).
M-factor for acute aquatic toxicity: not need to be assigned
M-factor for chronic aquatic toxicity: not need to be assigned
Classification justification according to DSD of AES (C9 -11, 1-2.5EO) Na (CAS 160901-28-0):
Based on the data above, AES (C9 -11, 1-2.5EO) Na is considered to be rapidly degradable and has a low potential for bioaccumulation. The acute aquatic toxicity L(E)C50 values are above 1 mg/L for fish, invertebrates and algae. AES (C9 -11, 1-2.5EO) Na (CAS 160901-28-0) does not need to be classified and labeled as environmental hazard according to Directive 67/548/EEC.
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