Registration Dossier
Registration Dossier
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EC number: 500-465-4 | CAS number: 160901-28-0 1 - 2.5 moles ethoxylated
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to the Category Approach Justification provided in Section 13
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 16 h
- Dose descriptor:
- EC10
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth inhibition
- Duration:
- 16 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth inhibition
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Justification for type of information:
- Please refer to the Category Approach Justification provided in Section 13
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 16 h
- Dose descriptor:
- EC10
- Effect conc.:
- > 10 g/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth inhibition
- Duration:
- 16 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 g/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- growth inhibition
Referenceopen allclose all
Description of key information
EC10 (16 h) > 10000 mg a.i./L (nominal) for Pseudomonas putida.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 10 000 mg/L
Additional information
For microorganisms no studies on toxic effects AES (C9 -11, 1 -2.5EO) Na (CAS 160901 -28 -0) are available. Therefore, a read-across approach from AES (C12 -14, 1 -2.5EO) Na (CAS 68891 -38 -3) and AES (C12 -14, 1 -2.5EO) MIPA (CAS 1187742 -72 -8) was applied.
Both studies were performed following the procedures of DIN 38412, part 8 and GLP. Based on growth inhibition EC10 values > 10000 mg/L for Pseudomonas putida were observed in both tests after 16 hours (Sasol, 1993, 1999).
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