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EC number: 500-465-4
CAS number: 160901-28-0
1 - 2.5 moles ethoxylated
The chemical safety assessment carried out according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish.
There are no long-term fish studies available for AES (C9-11,
1-2.5EO) Na (CAS 160901-28-0). Based on the available acute and chronic
toxicity data of alkyl ether sulfates, fish cannot be identified as the
most sensitive taxonomic group. According to the “Guidance on
information requirements and chemical safety assessment Chapter R.7b:
Endpoint specific guidance, R.126.96.36.199” (ECHA, 2008), long-term testing
of fish should only be conducted if it represents the most sensitive
taxonomic group. The Guidance Document states that if invertebrates are
likely to be more sensitive than fish and algae or the relative
sensitivity of invertebrates cannot be predicted, long-term testing on
Daphnia sp. should be preferred instead of fish.
For the structural comparable AES (C8-10, 1-2.5EO) NH4 the results
of a chronic invertebrates study carried out with Daphnia magna are
available. In this test a NOEC of 5.3 mg a.i./L was determined. Since
for the longer carbon chain lengths AES the available acute and chronic
results of fish and daphnids are in the same range, it can be assumed
that for the shorter carbon chain lengths AES the results of a long-term
fish study will not be significantly different from the results of the
available chronic Daphnia study. Hence, based on the information
discussed above and due to animal welfare reasons, no further long-term
test with fish is proposed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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