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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17 Dec 2018 to 07 Mar 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
March 04, 2016
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling Point)
Version / remarks:
July 27, 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Version / remarks:
August 1996
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
Appearance: Off-white powder
Purity/Composition: 98.8%
Test item storage: At room temperature
Key result
Decomposition:
yes
Decomp. temp.:
> 300 °C

Preliminary Test

The TGA curve of the test item is shown in Figure 1.  Starting at 275°C, the weight of the sample decreased significantly.  At 370°C, the sample weight had decreased by 25%.

After the experiment, a dark brown molten residue remained in the sample container (original colour: off white).  The change of the colour indicated reaction and/or decomposition of the test item.

Main Study

The DSC curve obtained with Experiment 1 is shown in Figure 2.  An endothermic effect was observed between 100°C and 150°C followed by an endothermic effect starting at 300°C.  The extrapolated onset temperature of the first effect was 127.975°C.  The endothermic effect was most likely obtained due to melting of the test item.  The second endothermic effect was probably obtained due to reaction and/or decomposition of the test item.

After the experiment, an amber molten residue remained in the sample container (original colour: off white).  The change of the colour indicated reaction and/or decomposition of the test item.  Based on this visual observation, it was found that the test item had molten and the change of the colour demonstrated reaction and/or decomposition of the test item.

In order to investigate the endothermic effect, Experiment 2 was stopped directly after the melting effect.  Figure 3 shows the DSC curve obtained.  The extrapolated onset temperature was 127.671°C.  After the experiment, a colourless molten residue remained in the sample container (original colour: off white) It demonstrated that melting was the reason for the endothermic effect.

The melting temperature was determined as the mean melting temperature of Experiment 1 (127.975°C) and Experiment 2 (127.671°C).

Conclusions:
The boiling temperature of 2-Benzoylbenzoic acid was determined by DSC.

Reaction and/or decomposition of the test item was observed during DSC experiment at temperatures of > 300°C (> 573K).  Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started.  Based on this, the test item has no boiling temperature.
Executive summary:

In this guideline (OECD 103) study conducted with GLP certification, the test material (EC 201-612-2) was determined to decompose at >300 °C (no boiling point).

Description of key information

Study conducted to recognised testing guidelines with GLP certification.

Key value for chemical safety assessment

Additional information

Decomposes at >300 °C