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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17 Dec 2018 to 07 Mar 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
March 04, 2016
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
July 27, 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Version / remarks:
March 1998
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
Appearance: Off-white powder
Purity/Composition: 98.8%
Test item storage: At room temperature
Key result
Melting / freezing pt.:
127.8 °C

Preliminary Test

The TGA curve of the test item is shown in Figure 1.  Starting at 275°C, the weight of the sample decreased significantly.  At 370°C, the sample weight had decreased by 25%.

After the experiment, a dark brown molten residue remained in the sample container (original colour: off white).  The change of the colour indicated reaction and/or decomposition of the test item.

Main Study

The DSC curve obtained with Experiment 1 is shown in Figure 2.  An endothermic effect was observed between 100°C and 150°C followed by an endothermic effect starting at 300°C.  The extrapolated onset temperature of the first effect was 127.975°C.  The endothermic effect was most likely obtained due to melting of the test item.  The second endothermic effect was probably obtained due to reaction and/or decomposition of the test item.

After the experiment, an amber molten residue remained in the sample container (original colour: off white).  The change of the colour indicated reaction and/or decomposition of the test item.  Based on this visual observation, it was found that the test item had molten and the change of the colour demonstrated reaction and/or decomposition of the test item.

In order to investigate the endothermic effect, Experiment 2 was stopped directly after the melting effect.  Figure 3 shows the DSC curve obtained.  The extrapolated onset temperature was 127.671°C.  After the experiment, a colourless molten residue remained in the sample container (original colour: off white) It demonstrated that melting was the reason for the endothermic effect.

The melting temperature was determined as the mean melting temperature of Experiment 1 (127.975°C) and Experiment 2 (127.671°C).

Conclusions:
The melting temperature of 2-Benzoylbenzoic acid was determined by DSC.

The melting temperature of the test item was 127.8°C (401.0K).
Executive summary:

In this guideline (OECD 102) study conducted with GLP certification, the melting point of the test material (EC 201-612-2) was determined to be 127.8 °C

Description of key information

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
127.8 °C

Additional information