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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

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Reference
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2013-07-25 to 2013-09-04
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Dissociating properties:
not determined

The 0.1M sample solution (in water) was found to be close to neutral in pH tending more towards the acidic region. When titrated against both acid and base, the inflection point was reached instantly in both cases. Smaller additions were used when titrating; however the inflection point was still reached instantly. Testing therefore could not be carried out.

The 0.1M solutions were used due to the neutral pH of the test sample. Lower concentrations would simply display the pH of the water it was added to.

Conclusions:
The dissociation constant could not be determined.
Executive summary:

The dissociation constant was determined using the titration method.

The 0.1M sample solution (in water) was found to be close to neutral in pH tending more towards the acidic region. When titrated against both acid and base, the inflection point was reached instantly in both cases. Smaller additions were used when titrating; however the inflection point was still reached instantly. Testing therefore could not be carried out.

Description of key information

Dissociation constant (OECD 112): The dissociation constant could not be determined.

Key value for chemical safety assessment

Additional information

The dissociation constant was determined using the titration method.

The 0.1M sample solution (in water) was found to be close to neutral in pH tending more towards the acidic region. When titrated against both acid and base, the inflection point was reached instantly in both cases. Smaller additions were used when titrating; however the inflection point was still reached instantly. Testing therefore could not be carried out.