Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-281-9 | CAS number: -
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2009-11-16 to 2010-04-21
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- GLP study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- capillary method
- Key result
- Melting / freezing pt.:
- > 2 - < 90 °C
- Atm. press.:
- 1 atm
- Decomposition:
- no
- Sublimation:
- no
- Remarks on result:
- other: The viscosity of the test substance decreased throughout the whole test beginning at 2 °C. At about 90 °C the test substance was a colourless liquid of low viscosity. Due to these observations no melting point but a melting range was stated.
- Conclusions:
- The experimental determined melting range of the test substance is 2 °C to 90 °C.
- Executive summary:
The determination of the melting temperature of the test substance was performed by the capillary method with hot block heating.
At the start of the test at 2 °C the test substance was a highly viscous colourless non-stirrable mass. The viscosity of the test substance decreased throughout the whole test beginning at 2 °C. At about 90 °C the test substance was a colourless liquid of low viscosity. Due to these observations no melting point but a melting range was stated. The experimental determined melting range of the test substance is 2 °C to 90 °C.
- Endpoint:
- melting point/freezing point
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Study period:
- 2010-04-21
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- QSAR prediction
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- not applicable
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- not applicable
- Principles of method if other than guideline:
- Atom/fragment contribution method using the software MPBPWIN Version v1.43, provided by U.S. Environmental Protection Agency.
- GLP compliance:
- yes
- Type of method:
- other: Software MPBPWIN Version v1.43
- Key result
- Melting / freezing pt.:
- 33.8 °C
- Conclusions:
- The calculated melting point of the main constituent (3-Hydroxy-2-(hydroxymethyl)-2-methylpropionaldehyde) of the test substance using a QSAR-method is 33.8 °C.
- Executive summary:
The calculated melting point of the the main constituent (3-Hydroxy-2-(hydroxymethyl)-2-methylpropionaldehyde) of the test substance
using a QSAR-method is 33.8 °C.
Referenceopen allclose all
Description of key information
Melting Temperature ( OECD 102, EU Method A.1.) The experimental determined melting range of the test substance is 2 °C to 90 °C.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 33.8 °C
Additional information
The determination of the melting temperature of the test substance was performed by the capillary method with hot block heating.
At the start of the test at 2 °C the test substance was a highly viscous colourless non-stirrable mass. The viscosity of the test substance decreased throughout the whole test beginning at 2 °C. At about 90 °C the test substance was a colourless liquid of low viscosity. Due to these observations no melting point but a melting range was stated. The experimental determined melting range of the test substance is 2 °C to 90 °C.
In addition a supporting study was performed using a QSAR method. The calculated melting point of the the main constituent 3-Hydroxy-2-(hydroxymethyl)-2-methylpropionaldehyde)of the test substance using a QSAR-method is 33.8 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
