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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

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Description of key information

EC10 (3h) = 372 mg/L (nominal, based on active matter) for activated sludge (OECD 209)

Key value for chemical safety assessment

EC50 for microorganisms:
791 mg/L
EC10 or NOEC for microorganisms:
372 mg/L

Additional information

No studies investigating the toxicity of fatty acid chloride, C12, reaction product with sodium glutamate and sodium hydroxide to microorganisms are available. Thus, available data for the source substance Sodium N-cocoyl glycinate was used in a read across approach. The read across is considered valid as both substances are structurally similar, which assume very similar physico-chemical properties resulting in identical environmental behaviour and ecotoxicity.

A Respiration Inhibition Test with activated sludge according to OECD Guideline No. 209 was carried out with the test item Sodium N-cocoyl-glycinate. Test system was activated sludge of the municipal treatment plant of D-31137 Hildesheim. The test was carried out under static conditions with the nominal active ingredient concentrations 100 - 180 - 320 - 580 - 1000 mg/L. The respiration rates of the control, reference and test item replicates were measured after a contact time of three hours, and the inhibitory effects of the test and reference item were determined in comparison to the control respiration rates. The mean inhibition of respiration for the test item replicates ranged from -33 % to 62 %.

The NOEC of the active ingredient is 320 mg/L, the EC10 is 372 mg/L and the EC50 791 mg/L to activated sludge of a municipal sewage treatment plant.