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Environmental fate & pathways

Hydrolysis

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Link to relevant study record(s)

Reference
Endpoint:
hydrolysis
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is readily biodegradable

Description of key information

Hydrolysis is not a relevant degradation pathway.

Key value for chemical safety assessment

Additional information

No experimental data evaluating the hydrolysis of Disodium N-lauroyl-L-glutamate are available. However, according to Regulation (EC) No. 1907/2006, Annex VIII, column 2 (9.2.2.1), testing hydrolysis as a function of pH is not required since the substance is readily biodegradable.

Nevertheless, most amides hydrolyze to acids extremely slowly under environmental conditions with half-lives measured in centuries. Electronegative groups on carbon or nitrogen greatly accelerate base catalyzed hydrolysis, but alkyl groups on nitrogen retard both acid and base catalyzed processes (Mabey and Mill, 1978). Thus, hydrolysis is not considered to be a relevant degradation pathway for Disodium N-lauroyl-L-glutamate in the aquatic environment.

Mabey W & Mill T. 1978. Critical review of hydrolysis of organic compounds in water under environmental conditions. J Phys Chem Ref Data 7(2): 383-415

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