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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
10.-22.06.2016
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
not performed according to GLP
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Key result
Water solubility:
1.25 g/L
Conc. based on:
test mat. (total fraction)
Loading of aqueous phase:
50 g/L
Incubation duration:
72 h
Temp.:
30 °C
pH:
3.38
Remarks on result:
other: Mean value of three measurements.
Details on results:
Results: Preliminary test, water solubility: 1-10 g/L
Sample 1, 24 h: water solubility = 1.22 g/L, pH = 3.41
Sample 2, 48 h: water solubility = 1.25 g/L, pH = 3.39
Sample 3, 72 h: water solubility = 1.29 g/L, pH = 3.33
Values 1-3 are used for the calculation of the average of values.
Water solubility = 1.25 g/l
pH = 3.38
Conclusions:
The solubility of m-toluic acid was 1.25 g/L at 30°C under these experimental conditions.

Description of key information

The solubility of m-toluic acid was determined with 1.25 g/L at 30 °C in a test according to A.6 ‘flask method’ of Regulation (EC) No 440/2008.

Key value for chemical safety assessment

Water solubility:
1.25 g/L
at the temperature of:
30 °C

Additional information