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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study planned
Qualifier:
according to
Guideline:
OECD Guideline 211 (Daphnia magna Reproduction Test)
Deviations:
no

Description of key information

The water solubility of the registered substance was determined in accordance with the OECD Testing Guideline 105. The study concluded that Calcium Titanium Trioxide is poorly soluble in water (<0.3 mg/L).

As the substance is poorly soluble in water a long-term aquatic toxicity study should be considered instead of short-term studies. Therefore, short-term toxicity to algae and aquatic invertebrates were waived in accordance with Annex VII of REACH.

During the OECD 105 it could not be excluded that nanoparticles of Calcium Titanium Trioxide will be available as a suspension in water. Therefore, due to its poorly soluble properties and to lack of certainty on of suspended nanoparticles of Calcium Titanium Trioxide in water, a long term Daphnia Reproduction Test in accordance with the OECD Testing Guideline 211 is proposed (Annex IX of REACH).

Key value for chemical safety assessment

Additional information