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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation, other
Type of information:
other: expert assessment
Adequacy of study:
key study
Study period:
12 March 2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An assessment was performed based on available information on the substance and experimental data on a suitable analogue.

Data source

Reference
Reference Type:
other: expert assessment
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
An assessment was performed based on available information on the substance and experimental data on a suitable analogue.
GLP compliance:
no
Type of study:
other: An assessment was performed based on available information on the substance and experimental data on a suitable analogue.

Test material

Constituent 1
Chemical structure
Reference substance name:
Calcium titanium trioxide
EC Number:
234-988-1
EC Name:
Calcium titanium trioxide
Cas Number:
12049-50-2
Molecular formula:
Ca.O3Ti
IUPAC Name:
Calcium titanium trioxide
impurity 1
Chemical structure
Reference substance name:
Titanium dioxide
EC Number:
236-675-5
EC Name:
Titanium dioxide
Cas Number:
13463-67-7
Molecular formula:
O2Ti
IUPAC Name:
dioxotitanium
impurity 2
Chemical structure
Reference substance name:
Silicon dioxide
EC Number:
231-545-4
EC Name:
Silicon dioxide
Cas Number:
7631-86-9
Molecular formula:
O2Si
IUPAC Name:
Silicon dioxide
impurity 3
Chemical structure
Reference substance name:
Aluminium oxide
EC Number:
215-691-6
EC Name:
Aluminium oxide
Cas Number:
1344-28-1
Molecular formula:
Al2O3
IUPAC Name:
oxo(oxoalumanyloxy)alumane
impurity 4
Chemical structure
Reference substance name:
Magnesium oxide
EC Number:
215-171-9
EC Name:
Magnesium oxide
Cas Number:
1309-48-4
Molecular formula:
MgO
IUPAC Name:
magnesium oxygen(-2) anion
impurity 5
Chemical structure
Reference substance name:
Diniobium pentaoxide
EC Number:
215-213-6
EC Name:
Diniobium pentaoxide
Cas Number:
1313-96-8
Molecular formula:
Nb2O5
IUPAC Name:
diniobium pentoxide
Test material form:
solid: nanoform, surface-treated

Results and discussion

In vivo (non-LLNA)

Results
Key result
Remarks on result:
other: Calcium Titanium Trioxide is not expected to induce skin sensitisation

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
Calcium Titanium Trioxide is not expected to induce skin sensitisation.
Executive summary:

An assessment was performed based on available information on the substance and experimental data on a suitable analogue. It concluded that Calcium Titanium Trioxide is not expected to induce skin sensitisation.